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phrK [2018-11-07 15:39:34]
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phrK [2018-11-07 15:39:34]

response regulator aspartate phosphatase (RapK) regulator, controls ComA activity
locus
BSU18920
pI
8.16
mw
3.98 kDa
protein length
40 aa Sequence Blast
gene length
120 bp Sequence Blast
function
control of ComA activity
product
phosphatase (RapK) regulator
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.7|Genetic competence]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.3|Control of response regulators/ other]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.8|Quorum sensing]
  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.3|Genetic competence]
  • [category|SW 6|Groups of genes] → [category|SW 6.8|Short peptides]

    • Gene

    Coordinates
    2,063,262 → 2,063,384

    The protein

    Catalyzed reaction/ biological activity

  • inhibits [protein|C8BF3815578293542D14811C60F4CA78AACF73EB|RapK] activity [Pubmed|16816200]

    • Protein family

  • RAP family (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|C8BF3815578293542D14811C60F4CA78AACF73EB|rapK]-[gene|886C1BAE024A9D1A6C7C4F16E5251D5427B8D41E|phrK]
    description
    [Pubmed|11466295]

    sigma factors

  • [protein|DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|SigH]: sigma factor, [Pubmed|11466295], in [regulon|DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|SigH regulon]

    • regulatory mechanism

  • [protein|638D6D2FCCA2A167EFED05CB4E60C2D78D5319AE|PhoP]: activation, [Pubmed|25666134], in [regulon|638D6D2FCCA2A167EFED05CB4E60C2D78D5319AE|PhoP regulon]
  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|20817675], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]

    • regulation

  • induced under conditions of phosphate limitation ([protein|search|PhoP]) [Pubmed|25666134]
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    Biological materials

    Mutant

  • BKE18920 (Δ[gene|886C1BAE024A9D1A6C7C4F16E5251D5427B8D41E|phrK]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE18920 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTTCATAAGATTCCCTCCAC, downstream forward: _UP4_TAAAAAAGGTTGATTAATTA
  • BKK18920 (Δ[gene|886C1BAE024A9D1A6C7C4F16E5251D5427B8D41E|phrK]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK18920 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTTCATAAGATTCCCTCCAC, downstream forward: _UP4_TAAAAAAGGTTGATTAATTA

    • References

  • 11466295,16816200,20817675